- "A can of bolognese. Expired. If consumed, the individual will become violently sick and find a location to throw up in."― In-game Description
- World of Tomorrow - Found in multiple places throughout Villa Caruso, including the kitchen pantry, a storeroom adjoining the wine cellar, and in the attic.
- Nightcall - Found on a shelf in the basement hallway.
- Three-Headed Serpent - Found on a shelf in the store opposite the Doctor's Office.
- The Ark Society - Found in a trash can just outside the kitchen in the Cellar.
- Unlike most poisons the Expired Can of Spaghetti Sauce can also be used as a non-lethal melee weapon and distraction.
- Isabella Caruso's signature dish was her famous bolognese made from her family recipe. However the secret to the recipe was in fact pre-made cans of spaghetti sauce.
- Silvio Caruso enjoys his lunch containing the spaghetti sauce, despite the cans having expired.
- The sauce's brand name, "Molto Bene", is Italian for "very good".