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Patient Zero is the fourth, final and titular mission of the Patient Zero bonus campaign, featured in HITMAN™ - Game of the Year Edition.

Objectives:

Description

The mission primarily takes place within and around the main surgery room of the Hokkaido GAMA facility. Owen Cage, being highly contagious, must be kept in isolation and as such the facility has been altered to do so.

Despite being isolated, the Nabazov virus will begin spreading from Owen Cage to other people present in the mission if the player does not intervene. The virus can potentially spread to every NPC within the mission area; anyone not wearing a Bio Suit can be infected given they come in close enough contact to an infected NPC. All those infected with the virus become additional targets.

47 can also become infected with the virus. If the player makes direct contact with Owen Cage without wearing either the Bio Suit disguise or Head Researcher disguise, 47 will become infected and the player must locate and use the virus' vaccine before leaving the mission. If five minutes pass before the vaccine is used, 47 will die and the mission will fail.

Mission Briefing


"You have two targets.

First, Owen Cage, the rogue viral researcher responsible for the weaponization of the Nabazov virus. Cage was moved to the Hokkaido GAMA facility by Japanese authorities. All evidence indicates that he infected himself, intending to become Patient Zero.

He is currently being kept alive in isolation by your second target, Klaus Liebleid. An Ether Corporation scientist, Dr. Liebleid is trying to extract as much information about the virus as possible before Owen Cage dies.

We cannot allow Ether to succeed in reverse engineering the virus and profiting from it. Your task is simple, 47. Contain the virus by eliminating Cage and Liebleid. Whatever happens, the Nabazov virus must be destroyed. We must contain it here, no matter the cost. I'll leave you to prepare."
― In-Game Briefing

Opportunities

There are no opportunities in this mission.

Intelligence

  • A Weaponized Virus
The following contain spoilers. Click "show" to continue.

These notes show the doctor's exploration of the weaponised virus' infection rates and lethality. He believes it to be intended to attack built up areas such as cities, while leaving sparsely populated areas relatively unaffected. He seems to admire the craftmanship.

  • Examination Schedule
The following contain spoilers. Click "show" to continue.

Patient Zero is to be brought for examination in the theatre at regular intervals. Ensure full biohazard protocols are followed at all times when in close proximity.

  • Necrotic Die-Off
The following contain spoilers. Click "show" to continue.

These notes indicate that the virus dies off rapidly as soon as the host-body dies. Essentially, eliminating someone will immediately end the risk of infection.

  • The Antidote
The following contain spoilers. Click "show" to continue.

Head researcher Klaus Leibleid has developed an antidote for his private use. It's stored with the Stem Cell supplies near the Hospital furnace room.

Challenges

Patient Zero, as well as other missions featured in the Patient Zero campaign, have no mastery points for their mission specific challenges.

Type Key: A=Assassination; F=Feats
Name Type Description Reward
Suit Only A
  • Assassinate the targets and complete the mission.
  • Do it all in your suit.
NA
Sniper Assassin A
  •  Complete "Patient Zero" .
  • Assassinate all targets with a sniper rifle.
  • Only kill the targets.
  • Do not get spotted.
  • If you are detected by cameras, erase or destroy the evidence.
NA
Needle Work A Assassinate Owen Cage with a lethal injection dressed as Klaus Liebleid in the main surgery room. NA
Silent Assassin A
  • Complete "Patient Zero".
  • Only kill the targets.
  • No bodies found.
  • Do not get spotted.
  • If you are detected by cameras, erase or destroy the evidence.
NA
No Evidence A
  • Complete "Patient Zero" with no bodies found.
  • If you are detected by cameras, erase or destroy the evidence.
NA
Silent Assassin, Suit Only A
  • Complete "Patient Zero".
  • Only kill the targets.
  • No bodies found.
  • Do not get spotted.
  • If you are detected by cameras, erase or destroy the evidence.
  • Do it all in your suit.
NA
Inferno A Assassinate Owen Cage and Klaus Liebleid using the incineration procedure without any other casualties. NA
Lucky Shot F
  • Contact the Nabazov Virus.
  • Cure 47 of the Nabazov Virus with 10 seconds or less remaining until 47's death.
NA
No Rubber F Complete the mission without using a Hazmat Suit. NA
Containment F Complete the mission with no one being infected by Nabazov Virus. NA
You Know the Number F
  • Complete Patient Zero.
  • Kill at least 47 people infected with the Nabazov Virus besides Owen Cage.
NA

Disguises

Weapons

Firearms

Melee

Other

Missions in HITMAN™
Season One
Training (Greenland) Freeform Training - The Final Test
France The Showstopper - Holiday Hoarders
Italy World of Tomorrow - The Icon - Landslide
Morocco A Gilded Cage - A House Built on Sand
Thailand Club 27
United States of America Freedom Fighters
Japan Situs Inversus
Patient Zero
Thailand The Source
Italy The Author
United States of America The Vector
Japan Patient Zero
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